Endocrine Abstracts

Aims: The prevalence of type 2 diabetes due to insulin resistance is increasing in puberty. Authors have investigated whether body weight excess arises only from increased fat content of the body. Different anthropometrical data were also analysed if they are able to predict degree of insulin resistance.Materials and methods: 108 obese children (50 female, 58 male, Tanner st-s1-5, mean age 12.06 years, mean BMI: 30.97 kg/m2) with positive fami...

Growth hormone deficient (GHD) children born small-for-gestational-age (SGA) receive the same hGH dose as the children born with appropriate weight/length for gestational age (AGA). There are very few data on their lower growth response to the usual GH replacement dose. The aim of this multi-centre retrospective study is to analyse the hGH dose dependency of GHD children with SGA.SGA was defined as a birth weight/length below – 2 SD for gestational ...